Since 1958 Antonakos’s work has been seen in hundreds of solo and group shows in New York, around the USA, Europe, and Japan. For almost every exhibition, he created new work. Antonakos: A Retrospective was held in 2007-8 at the Benaki Museum Piraeus and was accompanied by a major catalogue. It traveled to the Allentown (PA) Museum of Art in 2008. Irving Sandler’s comprehensive monograph Antonakos was published in 1999. A major monograph will be released by Rizzoli in fall 2023.

Large-scale neon installations were exhibited at documenta 6, 1977; the Sao Paulo Bienale, 1987; Artec ’89, Nagoya, Japan, 1989; the XLVII Venice Biennale, 1997; the Aeschyleia Festival in Elefsina, 2011; documenta 14, 2017; several Whitney Annuals, NYC starting in 1966; — and in such institutions as the Stedelijk van Abbemuseum, Eindhoven, The Netherlands; the Loeb Student Center, NYU, NYC, 1967; the Nelson Gallery of Art, Kansas City, MO, 1968; the Grand Rapids Art Museum, Grand Rapids, MICHIGAN,1974; the San Francisco Museum of Art, 1974; the Fort Worth Art Museum (1974); the Albright-Knox Art Gallery, Buffalo, NY, 1974; the Lowe Art Museum, Miami (1980); the Washington Project for the Arts, Wash. DC, 1981; Creative Time, NYC, 1981; the Palais des Beaux-Arts, Brussels,1982; the Museum of Modern Art of the City of Paris, 1983; the La Jolla MCA,1984; the Rose Art Museum, Brandeis U., Waltham, MA, 1986 and 2000; Artec89, Nagoya, Japan; the National Gallery — Alexandros Soutzos Museum, Athens, 1992; Harvard’s Carpenter Center, 1992-93; the Fortress of St. George, Rhodes,1993; P.S.1 Center for Contemporary Art, LIC, NY, 1999; the Chrysler Museum, Norfolk, VA,1999; the Neuberger Museum, SUNY, Purchase, NY, 2000 and 2018; the Schirn Kunsthalle, Frankfurt, 2001; Lafayette College, Easton, PA, 2004; the Kydoniefs Foundation, Andros, Greece, 2004; the Chapel of St. George, Mystras, Greece, 2004; the Alexander S. Onassis Foundation, Athens, 2011; the Grand Palais, Paris, 2013; Industry City, Brooklyn, 2013; and the Hainan Biennale, Hainan, China, 2021.

Major solo museum shows include Collages and Assemblages, Miami MoMa, Miami, Fl, 1964; Pillows, Contemp. Art Mus., Houston, TX, 1971; Neons, Allen Priebe Art Gallery, Wisconsin State Univ., Oshkosh, WI, 1971; California Show, Fresno State College Art Gallery, Fresno, CA, 1972, Ten Outdoor Neons, Fort Worth Art Museum, Fort Worth, TX, 1974; Recent Drawings and Sculpture, Albright Knox Art Gall., Buffalo, NY, 1974; Three Neon Walls, Lowe Art Museum, Miami, Fl., 1980; Neons for Nevers, Maison de Culture de Nevers, Never, France, 1983; The Room, the Art Institute of Boston, Boston, MA, 1996; Inner Light, Smith College MoA, Northampton, MA; 1997; Meditation Room, Samuel P. Harn MoA, Gainesville, Fl, 1997; Public Work and Praise, State MoCA, Thessaloniki, 2000; Time Boxes 2000, Rose Art Museum, Brandeis Univ., Waltham, MA, 2000; Proscenium, the Neuberger Museum, SUNY, Purchase, 2000 and 2018; Journey, Macedonian MoMA, Thessaloniki, 2003; Silent Chapel, Onassis Cultural Center, NYC, 2003—4; S.A.: Three Spaces/Four Directions, Lafayette College, Easton, PA, 2004; Remembrance, Chapel of St. George, Mystras, Greece, 2004; Five Decades of Drawing, Graduate Center, CUNY, NYC, 2005; The Room Chapel, Allentown MoA, Allentown, PA, 2018-2020; Light: S.A. and the Russian Avant-Garde, MOMus Museum Alex Mylona, Athens, 2020; and FORM COLOR SPACE, French Institute Alliance Française, NYC, 2022.

The over fifty Public Works include Red Neon Circle Fragments on a Blue Wall, 1978, Dayton, OH; Incomplete Circles and Squares, Red Neon, Hampshire College, Amherst, Ma, 1978; 
Incomplete Red Neon Square on Exterior Corner (for Chris D’Arcangelo) Univ. of Mass., Amherst, MA, 1979; Four Walls for the Hartsfield Int’l. Airport, Atlanta, GA, 1980; Neon for 42nd Street, NYC, 1981; Neon for the Bagley Wright Theater, Seattle, WA, 1983; Neons for the Tacoma Dome, Tacoma, WA, 1984; Neon for the La Jolla MCA, La Jolla, CA, 1984; Neon for the 14th District Police Station, Chicago, IL, 1986; Neons for Exchange Place, Jersey City, NJ, 1989; Neon for the 59th Street Marine Transfer Station, NYC, 1990; Neons for Pershing Square, Los Angels, CA, 1991; Neons for the Stadtsparkasse, Cologne, 1993; Neons for Tachikawa, Japan, 1994; Blue Room, Public Library, San Antonio, TX, 1995; Neon for Granpark,Tokyo, Japan, 1996; Neon Lintel, Neuberger MoA, SUNY, Purchase, NY; Neons for Reading Power Plant, Tel Aviv, 1998-99; Procession, Ambelokipi Metro, Athens, 2000; Tria, Macedonian MCA, Thessaloniki, 2002; Six Incomplete Circles, Bari, Italy, 2004; Two Entrances, Athena Atrium, Odessa, 2004; Orrizonte, Airport of Puglia, Bari, 2005; Welcome, Univ of Dijon, France, 2006; and Recurrence, Hellenic American Union, Athens; 2007.

His work is in the collections of The Museum of Modern Art; the Whitney Museum of American Art; The Metropolitan Museum of Art; The Morgan Library & Museum; the New York University Art Collection; The National Gallery of Art; the Menil Collection Houston, TX; the Cleveland Museum of Art; the Dallas Museum of Art; The Smith College Museum of Art; the Los Angeles County MoA; The Wadsworth Atheneum Museum, Hartford, CT; the Parrish MoA, Southampton, NY; the National MCA, Athens; the State MCA, Thessaloniki; the Byzantine and Christian Museum, Athens; The Alpha Bank Collection, Athens; the Alexander S. Onassis Collection, Athens; and the Museum of Modern Art of the City of Paris.

He received the Prize for Art from the American Academy of Arts and Letters (2009) and Lifetime Achievement Awards from the Neuberger Museum, Purchase, NY (2000), the National Academy Museum and the Greek America Foundation (both 2011).